WebJun 5, 2024 · Now, two recent papers from researchers at Denali Therapeutics describe a novel modular platform capable of trafficking protein therapeutics to the brain through binding to transferrin receptor (TfR). WebProduct overview. Human Transferrin Receptor ELISA kit (ab272469) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of Human Transferrin Receptor protein in serum, plasma, urine, saliva, cell culture supernatant and cell and tissue extracts. It uses our proprietary SimpleStep ELISA® technology.
6Y76: AP01 - a redesigned transferrin receptor apical domain - RCSB
WebJul 30, 2024 · Iron-loaded transferrin binds with transferrin receptor 1 (TfR1) on the surface of cells, which then delivers the iron into the cell . TfR1 mediates cellular iron uptake, and as such, is a key molecule in cellular iron homeostasis and plays a central part in the homeostasis of the intestine [ 9 , 10 ]. WebJun 18, 2024 · Transferrin receptor expression in non-malignant and malignant human breast tissue. J Pathol. 2005;148:217–24. Shinohara H, Fan D, Ozawa S, Yano S, Van Arsdell M, Viner J, et al. Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin. chute middle school
The transferrin receptor: the cellular iron gate - OUP Academic
WebTransferrin receptor (TfR) is a transmembrane glycoprotein.8 Iron is transported by binding to specific TfR-transferrin complex and thereby released into cells.9 Through proteolysis, … WebAug 3, 2024 · Out of more than 200 candidate factors, researchers identified a glycoprotein called transferrin to be a procoagulant (a cause of blood clotting) that increases with age, ... WebFeb 28, 2024 · Camp ER Wang C Little EC Transferrin receptor targeting nanomedicine delivering wild-type p53 gene sensitizes pancreatic cancer to gemcitabine therapy Cancer Gene Ther 2013 204 222 228 23470564 , [Web of Science ®], [Google Scholar] dfs cream leather sofas