Crystal-storing histiocytosis kidney

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August undefined, 2024

WebCrystal-bearing or crystal-storing histiocytosis (CSH) is a rare mor-phologic manifestation of monoclonal gammopathy in which monoclonal crystals, usually belonging to kappa subtype and having various geometric shapes, collect within histiocytes that, via systemic circulation, end up in various organs [2-9]. In the kidney, such histio- WebMar 20, 2012 · Crystal-storing histiocytosis (CSH) is a rare finding characterized by intra-lysosomal accumulation of crystalline material in the histiocyte cytoplasm. 1 The crystals often consist of...

Crystal-storing histiocytosis - Wikipedia

WebNational Center for Biotechnology Information WebCrystal-storing histiocytosis (CSH) is a rare complication of MM and other B-lymphocyte proliferative diseases, and can involve a wide variety of organs. The most common target is bone marrow, followed by the head and neck, with kidney ranking third [ 3 ]. portsmouth water and sewage

Crystal-storing histiocytosis and crystalline tissue deposition in ...

WebWe have observed this histiocytic/foamy glomerular change on the kidney biopsy specimen in 5 different disease entities: crystal-storing histiocytosis, histiocytic glomerulopathy associated with macrophage-activating syndrome, thrombotic microangiopathy, lecithin-cholesterol acyltransferase deﬁ- ciency, and lipoprotein glomerulopathy. WebOct 20, 2024 · Crystal-storing histiocytosis (CSH) is an uncommon condition in which histiocytes accumulate a crystalline matter within their cytoplasm. Generally, those crystals are composed of either monoclonal or polyclonal immunoglobulin chains, which have a strong association with an underlying lymphoproliferative or plasma cell disorder (LP-PCD). WebApr 12, 2024 · Die Bezeichnung monoklonale Gammopathie renaler Signifikanz (MGRS) wurde vor einigen Jahren als neuer Oberbegriff eingeführt für Nierenerkrankungen durch Produktion von monoklonalen Immunglobulinen eines B‑Zell-Klons, der nicht die Kriterien für … oracle date minus 1 month

Crystal-storing histiocytosis involving the kidney in a low …

Multiple myeloma with crystal-storing histiocytosis, crystalline ...

Crystal-storing histiocytosis is a form of histiocytosis which mostly occurs in people with monoclonal gammopathies. Histiocytosis is an excessive number of histiocytes (an immune cell type which is part of the mononuclear phagocyte system). In the vast majority of crystal-storing histiocytosis cases (over 90%), immunoglobulins accumulate within the cytoplasm of histiocytes; in rare cases clofazimine, cystine, silica, or Charcot–Leyden crystals may be found in the histiocyte… WebMay 25, 2024 · The bone marrow is the most common site of histiocytes accumulation, whereas histiocytes containing crystals in the kidney have rarely been reported. Patients … portsmouth water department ohioWebFeb 15, 2015 · Crystal-storing histiocytosis (CSH) is a rare complication of monoclonal gammopathies caused by accu ... Sethi S, Cuiffo BP, Pinkus GS, et al. Crystal-storing histiocytosis involving the kidney in a low-grade B-cell lymphoproliferative disorder. Am J Kidney Dis 2002; 39:183–188. portsmouth water billing

"WebCrystal-storing histiocytosis is seen in patients with multiple myeloma and lymphoproliferative disorders; it is characterized by an accumulation of light chain … " - Crystal-storing histiocytosis kidney

Crystal-storing histiocytosis kidney

Histiocytic Glomerulopathy With Noncrystalline Inclusion …

WebAffiliations 1 Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; 2 Department of Pathology, Memorial Sloan-Kettering Cancer … WebFeb 15, 2024 · Considering that light-chain proximal tubulopathy (LCPT) can be classified into crystalline and noncrystalline subtypes, we thought that this case could be diagnosed as “histiocytic glomerulopathy with non-crystalline inclusion” or …

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WebFeb 20, 2024 · Studies of the biology of crystal handling by the kidney have shown that the formation of different crystals and other microparticles and the associated mechanisms … WebWe report a case of crystal-storing histiocytosis affecting the kidney with prominent infiltration of the mesangium by large mononuclear and multinuclear cells that contained …

WebCrystal-storing histiocytosis involving the kidney in a low-grade B-cell lymphoproliferative disorder Abstract. Intracellular crystal formation in histiocytes in multiple myeloma and … WebAug 30, 2024 · Crystal sorting histiocytosis (CSH) is a rare disorder that is morphologically characterized by the accumulation of monoclonal immunoglobulin crystals, predominantly of a kappa light chain type, within lysosomes of macrophages. CSH may result in a variety of clinical manifestations depending on the involved organs.

WebNov 19, 2015 · histiocytic/foamy glomerular change on the kidney biopsy specimen in 5 different disease entities: crystal-storing histiocytosis, histiocytic glomerulopathy … WebJan 1, 2002 · Although crystal-storing histiocytosis has been reported in the bone marrow and several organs in association with plasmacytic tumors, there is only one report in …

WebJan 29, 2024 · Crystal-storing histiocytosis (CSH) is a rare disorder characterized by the accumulation of nonneoplastic histiocytes containing intracytoplasmic refractile …

WebMar 5, 2024 · The kidney biopsy revealed light chain proximal tubulopathy (LCPT) with crystals, light chain crystal podocytopathy (LCCP), crystal-storing histiocytosis (CSH), and light chain cast nephropathy (LCCN). Of note, LCCP … oracle date hh24WebDec 28, 2024 · Crystal-storing histiocytosis may result in a variety of clinical manifestations depending on the involved organs. Eye/orbit is 1 of the most common sites affected by CSH. [ 12 ] Involvement of the cornea (“crystalline keratopathy”) is well described, and CSH has been also reported to involve the conjunctiva, the orbital fat, and extra ... oracle date format single digit monthWebCrystal-storing histiocytosis (CSH) is a rare disorder characterized by the accumulation of nonneoplastic histiocytes con-taining intracytoplasmic crystallized immunoglobulins. In … oracle date range in where clauseWebAug 1, 2024 · Crystal-storing histiocytosis (CSH) is an extremely rare disorder in which immunoglobulins accumulate abnormally in the cytoplasm of histiocytes, appearing as … portsmouth water hose pipe bandWebFeb 15, 2024 · Two years after diagnosis her kidney function remained normal, urinary protein level decreased to 1 g/day, and free light chain ratio decreased to 3.1. Key words crystal storing histiocytosis histiocytic glomerulopathy immunoelectron microscopy lysosome indigestion/constipation monoclonal gammopathy with renal significance (MGRS) oracle date function weekWebA case of crystal-storing histiocytosis (CSH) associated with mucosa-associated lymphoid tissue (MALT) lymphoma of orbit is reported. ... The possibility of a metastatic disease with possible primary sites as lung, breast, or kidney should be ruled out. Herein we report a case of adenocarcinoma arising from the RPE with a lung lesion suspicious ... oracle date to numberWebAug 1, 2024 · Crystal-storing histiocytosis is an extremely rare condition characterized by the accumulation of crystallized deposits in the cytoplasm of histiocytes. Out of 140 cases of CSH reported in a recent review, 122 cases (87%) were associated with an underlying lymphoproliferative, or plasma cell disorder (LP-PCD). portsmouth water annual report 2022